O-Desmethyltramadol

A opioid analgesic which is the main active metabolite of Tramadol. Alone, it is a few times more potent than Tramadol and has additional affinity for δ and κ-opioid receptors.

Harm potential

moderately addictive with a high potential for abuse

Dosage

This dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Duration

Effects

• euphoria
• dry mouth
• elevated mood
• itchiness
• feeling of relaxation
• constipation
• pupil constriction
• pain relief

Interactions

Tolerance

full

develops with prolonged and repeated use

half

3 - 7 days

zero

1 - 2 weeks